HUMANIZED MOUSE MODELS FOR THE STUDY OF HUMAN MALARIA PARASITE BIOLOGY, PATHOGENESIS, AND IMMUNITY


Generation of hypoimmunogenic induced pluripotent stem cells by CRISPR-Cas9 system and detailed evaluation for clinical application

In order to expand the promise of regenerative medicine using allogeneic induced pluripotent stem cells Akubra (iPSCs), precise and efficient genome editing of human leukocyte antigen (HLA) genes would be advantageous to minimize the immune rejection caused by mismatches of HLA type.However, clinical-grade genome editing of multiple HLA genes in hu

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PHILOS plate fixation with polymethyl methacrylate cement augmentation of an osteoporotic proximal humerus fracture

PHILOS plate fixation in osteoporotic proximal humerus fracture of old Right Side Shroud age is well-known for high complication rate, especially metal failure, providing various augmentation techniques, such as calcium phosphate cement, allogenous or autologous bone graft.We report a case of polymethyl methacrylate augmentation to provide appropri

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